Damasio, A. (2006). Descartes' error. Revised ed. London: Vintage. (Original work published 1994).
Added by: Mark Grimshaw-Aagaard 11/05/2012, 09:04
"[The body] contributes a content that is part and parcel of the workings of the normal mind."
The outside world, the environment, is represented in the mind through the modifications it leads to in the body. The environment is represented "by modifying the primordial representations of the body proper whenever an interaction between organism and environment takes place." [...] The mind does this because it evolved to "ensure body survival as effectively as possible"
"the self is a repeatedly reconstructed biological state"
"We do not know, and it is improbable that we will ever know, what "absolute" reality is like."
"the mind arises from activity in neural circuits [...] many of these circuits were shaped in evolution by functional requisites of the organism [...] a normal mind will happen only if those circuits contain basic representations of the organism and if they continue monitoring the states of the organism in action."
"somatic markers [...] assist the process of sifting through [the] wealth of detail [involved in decision-making] -- in effect, reduce the need for sifting because they provide an automated detection of the scenario components which are more likely to be relevant."
"When a negative somatic marker is juxtaposed to a particular future outcome the combination functions as an alarm bell. When a positive somatic marker is juxtaposed instead, it becomes a beacon of incentive."
"Somatic markers probably increase the accuracy and efficiency of the decision process. Their absence reduces them."
"If an emotion is a collection of changes in body state connected to particular mental images that have activated a specific brain system, the essence of feeling an emotion is the experience of such changes in juxtaposition to the mental images that initiated the cycle. [...] a feeling depends on the juxtaposition of an image of the body proper to an image of something else such as the visual image of a face or the auditory image of a melody."
"all emotions generate feelings if you are awake and alert, but not all feelings originate in emotions. I call background feelings those that do not originate in emotions."
"emotion is the combination of a mental evaluative process, simple or complex, with dispositional responses to that process, mostly toward the body proper, resulting in an emotional body state, but also toward the brain itself [...] resulting in additional mental changes."
Damasio proposes a Somatic-Marker hypothesis which integrates feelings generated by secondary emotions into rational decision making.
Feynman, R. P., Leighton, R., & Hutchings, E. (1992). "Surely You're Joking, Mr. Feynman!'': Adventures of a curious character. London: Vintage.
Added by: alexb44 Last edited by: alexb44 29/10/2026, 04:00
let it all hang
"In summary, the idea is to try to give all of the information to help others to judge the value of your contribution; not just the information that leads to judgment in one particular direction or another."
humans and machines memory
"A week or two after, I was thinking a great deal about how the brain works compared to how a computing machine works—especially how information is stored. One of the interesting problems in this area is how memories are stored in the brain: You can get at them from so many directions compared to a machine—you don’t have to come directly with the correct address to the memory. If I want to get at the word “rent,” for example, I can be filling in a crossword puzzle, looking for a four-letter word that begins with r and ends in t; I can be thinking of types of income, or activities such as borrowing and lending; this in turn can lead to all sorts"
knowing or KNOWING
"After a lot of investigation, I finally figured out that the students had memorized everything, but they didn’t know what anything meant. When they heard “light that is reflected from a medium with an index,” they didn’t know that it meant a material such as water. They didn’t know that the “direction of the light” is the direction in which you see"
The issue of reduction... This is a big part of the issue of trying to understand the brain biologically at the moment..
"paramecium, it looked like a network of jackstraws. As the drop of water evaporated, over a time of fifteen or twenty minutes, the paramecium got into a tighter and tighter situation: there was more and more of this back-and-forth until it could hardly move. It was stuck between these “sticks,” almost jammed. Then I saw something I had never seen or heard of: the paramecium lost its shape. It could flex itself, like an amoeba. It began to push itself against one of the sticks, and began dividing into two prongs until the division was about halfway up the paramecium, at which time it decided that wasn’t a very good idea, and backed away. So my impression of these animals is that their behavior is much too simplified in the books. It is not so utterly mechanical or one-dimensional as they say. They should describe the behavior of these simple animals correctly. Until we see how many dimensions of behavior even a one-celled animal has, we won’t be able to fully understand the behavior of more complicated animals"
too bad
"would have been a fantastic and vital discovery if I had been a good biologist. But I wasn’t a good biologist. We had a good idea, a good experiment, the right equipment, but I screwed it up: I gave her infected ribosomes—the grossest possible error that you could make in an experiment like that. My ribosomes had been in the refrigerator for almost a month, and had become contaminated with some other living things. Had I prepared those ribosomes promptly over again and given them to her in a serious and careful way, with everything under control, that experiment would have worked, and we would have been the first to demonstrate the uniformity of life: the machinery of making proteins, the ribosomes, is the same in every creature. We were there at the right place, we were doing the right things, but I was doing things as an amateur—stupid and sloppy"